Uncommon Medicines for Common Conditions by Dr. Nick Platamone
Sometimes, taking medicine can feel a little scary, but knowing how it works can make it less overwhelming. Atypical antipsychotics, also called second-generation antipsychotics (SGAs), are medicines that can help with serious mental health conditions like schizophrenia and bipolar disorder. They are also used for other things like depression, trouble sleeping, and even nightmares from PTSD.
How Do They Work?
These medicines help by changing the levels of two important chemicals in your brain: dopamine and serotonin.
Dopamine affects your mood and how you act.
Serotonin helps with mood, sleep, and anxiety.
By balancing these chemicals, SGAs can help you feel calmer, improve your mood, and help you sleep better.
Why Use These Medicines?
Even though SGAs are made for serious conditions like schizophrenia, doctors sometimes use them for other reasons, too.
Depression: If antidepressants aren’t helping enough, medicines like aripiprazole or brexpiprazole (Rexulti) might help.
Trouble sleeping: Low doses of quetiapine can help you fall asleep and stay asleep.
PTSD nightmares: Some SGAs can reduce bad dreams and help you sleep better if you have PTSD.
What Makes Them Different?
SGAs are often preferred over older types of antipsychotics because they usually have fewer serious side effects. For example, they’re less likely to cause muscle problems, like shaking or stiffness.
Side Effects to Watch For
Like any medicine, SGAs can have side effects, but not everyone gets them. Some common ones include:
Weight gain, especially with medicines like olanzapine or clozapine.
Feeling sleepy, especially with quetiapine.
SGAs can also affect things like your blood sugar or cholesterol. That’s why doctors may check your weight and run blood tests while you’re taking them.
Final Thoughts
Atypical antipsychotics can be helpful for many conditions, not just psychosis. They can improve mood, sleep, and even ease anxiety. At EuDoc, we understand that starting a new medicine can feel overwhelming. Through open conversations and deeper understanding, we take the time to address your concerns, explain how the medication can help, and discuss what to expect. You're not alone—our accessible and patient-centered care ensures we're here to guide you every step of the way.
Disclaimer: The information provided in this blog is for educational purposes only and is not intended as medical advice. While we hope it helps you understand your health a bit better, always check in with your healthcare provider before making any changes. If you’re looking for personalized, one-on-one care and want to dive deeper into your health, EuDoc can help! Sign up today for direct access to a primary care physician who knows you and your needs. No waiting rooms, no long phone trees—just the care you deserve, when you need it.
