The Hidden Heart Risk You’re Overlooking by Dr. Kenneth Qiu

You may have heard about cholesterol and how it can affect your heart, but there’s another type of cholesterol-related particle that is sometimes overlooked: Lp(a) which stands for lipoprotein (a) and which we call “L-P little a.” This unique protein has been getting a lot of attention recently because of its link to heart disease, stroke, and even aortic stenosis (AS), a heart valve problem. Here’s what you need to know about Lp(a) and why it matters to your health.

What is Lp(a)?

Lp(a) is a protein you inherit from your parents. You may have heard of LDL as the "bad" cholesterol that can build up in your blood vessels. Lp(a) gives these LDL particles armor and horns. The particles with the Lp(a) protein are harder for your liver to clear from your blood and they are more likely to end up in your blood vessels. While it’s only a small part of your total LDL cholesterol, Lp(a) can still cause problems. 

Why Does Lp(a) Matter?
Lp(a) is a risk factor for a few serious health problems, including:

  • Atherosclerosis: This is a condition where fatty deposits (plaque) build up in your arteries, making it harder for blood to flow. Lp(a) is linked to faster plaque buildup.

  • Aortic Stenosis (AS): This is a condition where the valve in your heart that controls blood flow from the heart to the rest of the body narrows. High levels of Lp(a) can speed up this process, and people with high Lp(a) may need a heart valve replacement sooner.

  • Coronary Artery Disease (CAD): plaque buildup in the heart which can lead to heart attacks

  • Carotid Stenosis: a narrowing of the arteries in your neck

  • Ischemic Stroke

How to Test for Lp(a)

A regular cholesterol test, called a lipid panel, won’t show you your Lp(a) levels. To find out if you have high Lp(a), you’ll need a special test. For those with elevated Lp(a), there are even more tests which can further stratify risk and tailor treatment. 

Final Thoughts

If you have a family history of heart disease or other risk factors like high cholesterol, looking into Lp(a) testing could be a good idea. With the right treatment, you can lower your risk and protect your heart for the future. While most doctors still do not do routine screening of Lp(a), all EuDoc patients get their Lp(a) level checked. This is consistent with the newest recommendation put out by the National Lipid Association. Early identification of Lp(a) status is important to managing long term health and exciting new medicines are coming soon to better manage Lp(a).

Disclaimer: The information provided in this blog is for educational purposes only and is not intended as medical advice. While we hope it helps you understand your health a bit better, always check in with your healthcare provider before making any changes. If you’re looking for personalized, one-on-one care and want to dive deeper into your health, EuDoc can help! Sign up today for direct access to a primary care physician who knows you and your needs. No waiting rooms, no long phone trees—just the care you deserve, when you need it.



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